Comparisons · 16 min read

Best Raw DNA Data Analysis Tools in 2026: 12 Sites Compared by Price, Privacy and Evidence

Twelve raw DNA data analysis tools compared on price, whether your file is uploaded or read in your browser, the evidence behind the results, and which files they accept.

Floriel FedryCo-founder & Software Engineer

If you want a readable health PDF from a file you already own, Full Human Health ($5, read in your browser, nothing uploaded) and Promethease ($25, uploaded) are the two literature-based picks. Genetic Genie is free for methylation panels. Genetic Lifehacks and GenomeInsight keep the file on your device too. SelfDecode has the most breadth but costs the most and stores your file. Allelix is open source for terminal users.

The 12 tools at a glance

We read each vendor's pages on 14 October 2026; prices change often, so each section links the page we used. "In your browser" means no copy of the file reaches the vendor; "uploaded" means one does, whatever happens to it afterwards.

ToolPriceWhere your file is processedEvidence sourceOutputAccepts
Full Human Health$5 per PDF, no subscriptionIn your browser, nothing uploadedGWAS Catalog (release 2026-06-01), PubMed link per rowPDF23andMe, AncestryDNA, MyHeritage, FTDNA, Living DNA, WeGene
Promethease$25 per report, +$4 per extra fileUploaded, deleted after the report is emailedSNPediaHTML report23andMe, AncestryDNA, FTDNA and others
Genetic GenieFree, donationsUploaded, kept up to 24 hoursCandidate-gene panels, ClinVarWeb tables23andMe, AncestryDNA, MyHeritage, FTDNA, Living DNA, WeGene, VCF
GenomeInsightFree tier, $49 one-timeIn your browserClinVar, GWAS Catalog, PharmGKB, CPIC named as sources; no study per rowWeb, PDF export23andMe, AncestryDNA, MyHeritage, FTDNA, VCF
Nebula / DNA Complete upload$19.95 per month or $49.95 per yearUploadedOwn reports after imputationWeb23andMe, AncestryDNA only
SelfDecodeBundles $499 to $899 with kit; upload price not on home pageUploaded and storedOwn imputation and polygenic risk pipelineWeb23 providers incl. 23andMe, AncestryDNA, MyHeritage
Sequencing.comUpload free; apps priced individually (reviews quote $5 to $179)Uploaded and storedVaries per appWeb, per app23andMe, AncestryDNA, MyHeritage, FTDNA
Genomelink100 traits free; $14 per month unlimitedUploaded and storedOwn trait libraryWeb dashboard23andMe, AncestryDNA, MyHeritage, FTDNA, Living DNA, WGS
LiveWello$19.95 one-time (per KnowYourDNA)Uploaded and storedSNP lists per category, no interpretationWeb23andMe, AncestryDNA, FTDNA, MyHeritage
Xcode Life$30 to $69 per report; packs $139 and $199Uploaded; delete any timeOwn curated reports, 718 traitsReports within 24 hours23andMe, AncestryDNA, MyHeritage, FTDNA, Living DNA
Genetic Lifehacks$17.99 per month, $79.99 per year or $179 lifetimeIn your browser420+ research articles with citationsWeb articles, printable summaries23andMe, AncestryDNA, MyHeritage, tellmeGen and others
AllelixFree, open source (AGPL)On your computer (CLI) or a browser demoClinVar, ClinPGx, GWAS Catalog, SNPediaHTML, JSON, terminal23andMe, AncestryDNA, MyHeritage, FTDNA, Living DNA, VCF

Not downloaded your file yet? Our guide to downloading raw DNA data from 23andMe, AncestryDNA and MyHeritage covers each provider. Keep a copy: several tools below delete it, and MyHeritage was not accepting third-party uploads as of August 2025 (MyHeritage Education, checked 14 October 2026).

Full Human Health

Full Human Health turns a 23andMe, AncestryDNA, MyHeritage, FamilyTreeDNA, Living DNA or WeGene export (.txt, .csv or .zip) into a PDF health report. The generator is Rust compiled to WebAssembly and runs in your browser tab: the file is parsed in memory and the PDF is written on your device, so nothing is uploaded. Our servers see an account and a credit balance, never the file. One credit is one PDF and costs $5, €5, £5 or CHF 5, with no subscription; a failed generation is refunded automatically. Rows come from the NHGRI-EBI GWAS Catalog filtered for genome-wide significance: 23,220 associations across 1,114 conditions and traits from 1,459 studies (release 2026-06-01), each with rsID, risk allele, your genotype, effect size and a PubMed link, as the sample report shows. It does not cover ancestry, pharmacogenomics, carrier status or candidate-gene SNPs such as MTHFR; the methodology page explains what is scored and how.

Promethease

Promethease connects your genotypes to the findings cited on SNPedia, the wiki that MyHeritage has owned together with Promethease since 2019. The home page states "Most reports cost $25", plus $4 to add another file to the same report (promethease.com, checked 14 October 2026). The file must be uploaded. The privacy policy, dated 15 April 2025, says file and report are deleted once the report has been emailed, that all previously stored files were deleted on 8 April 2025, and that DNA files count among the assets that would transfer in a business sale (promethease.com/privacy). The output is a dense HTML report you interpret yourself, ranked by SNPedia magnitude, and Genetic Lifehacks' raw-data guide (undated, checked 14 October 2026) describes SNPedia as "not as actively updated since ~2019" (geneticlifehacks.com). Our Promethease review and the Promethease alternatives roundup go deeper.

Genetic Genie

Genetic Genie is the free option: "Everything is anonymous and free!", donations welcome, no account needed (geneticgenie.org, checked 14 October 2026). It offers a Methylation Panel and a Detox Panel, which are candidate-gene lists (MTHFR, COMT and similar) rather than genome-wide results, plus GenVue Discovery, a ClinVar lookup. It accepts 23andMe, AncestryDNA, MyHeritage, FTDNA, Living DNA, WeGene and VCF files. The file is uploaded: the privacy policy, last modified 27 November 2019, says uploaded genetic information is kept for up to 24 hours and in most cases deleted right after processing (privacy policy). The result is a color-coded web table of genotypes without effect sizes. It is good for a quick look at methylation SNPs that GWAS-based reports, ours included, do not score, and weak as a health overview.

GenomeInsight

GenomeInsight runs in the browser: "Everything is processed inside your browser, so your DNA file never leaves your device" (genomeinsight.org, checked 14 October 2026). The free tier covers 30 traits, basic ancestry, a raw-data browser and PDF export with no account; Premium is a one-time $49 (launch pricing against $100) for 481 traits, 52 health conditions and pharmacogenomics for 14 genes, with a 30-day money-back guarantee (pricing). It accepts 23andMe and AncestryDNA .txt, MyHeritage .csv and VCF files, and the home page banner adds FamilyTreeDNA. The site names ClinVar, GWAS Catalog, PharmGKB and CPIC as its sources rather than a study per row; Genetic Lifehacks says the reports carry no references or study links. One caveat: Genetic Lifehacks' raw-data guide (undated, checked 14 October 2026) marks it "not recommended", citing a Blacklight scan that found Facebook and Google trackers despite the site's stated policy (geneticlifehacks.com). The no-upload claim is one you can check yourself with the test further down.

Nebula Genomics (DNA Complete) upload

Nebula Genomics used to accept free raw-data uploads for trait reports. KnowYourDNA reports that "Nebula Genomics shut down its consumer service on February 5, 2025" (updated 26 March 2026, knowyourdna.com), and Genomelink's October 2026 test says nebula.org now leads to DNA Complete (genomelink.io). Our check on 14 October 2026 agrees: nebula.org sells the DNA Complete whole-genome test "from $245", and dnacomplete.com/upload offers "DNA Expand", a paid imputation service at $49.95 per year or $19.95 per month, for AncestryDNA and 23andMe files only. We found no free upload tier on either site. DNA Complete Inc. is a subsidiary formed in 2024 by ProPhase Labs, which bought Nebula in 2021 (Wikipedia). The old free upload is gone; what replaced it is a subscription that takes a copy of your file.

SelfDecode

SelfDecode is the broadest platform here and the most expensive. The home page lists kit bundles at $499, $799 and $899, each with a SelfDecode DNA kit, and claims "1500+" health reports (selfdecode.com, checked 14 October 2026). Uploads are accepted from 23 providers including 23andMe, AncestryDNA, MyHeritage, Living DNA and FamilyTreeDNA, and its upload article says imputation "expands a 750,000-SNP file to 200M+ variants at about 99.7% accuracy" before the same polygenic risk pipeline runs (selfdecode.com article). The upload-only price is not on the home page; the help center notes a bundle price increase on 28 August 2026 (help center). Your file is uploaded and stored, and deletable on request. Where it wins: polygenic scores, imputation, lab integration and recommendations, none of which a $5 PDF attempts. Where it loses: price, a stored file and a subscription.

Sequencing.com

Sequencing.com is an app store for DNA files. Uploading and storing a raw file is free without a membership ("upload, download, and store your genetic data indefinitely, and for free", dnaweekly.com, June 2025, checked 14 October 2026). It accepts 23andMe, AncestryDNA, MyHeritage and FamilyTreeDNA files. Paid apps "typically cost $5 to $99 each" per KnowYourDNA (updated 21 August 2026, knowyourdna.com); Genomelink's October 2026 test puts reports at $29 to $179 and notes its free report had not arrived a week after upload. The company's own kits cost $69 for genotyping and about $399 for a whole genome. Evidence varies by app, because each app has its own author. Treat it as a marketplace: cheap to enter, easy to spend more in, and your file lives on its servers as long as the account exists.

Genomelink is traits first, health second. It gives 100 free traits after upload; the Unlimited Traits plan is $14 per month for 500+ traits (genomelink.io and its own tools guide, checked 14 October 2026). It accepts AncestryDNA, 23andMe, MyHeritage, FamilyTreeDNA, Living DNA and whole-genome files. The file is uploaded and stored; the site says you can delete it any time, and it discloses "standard web tracking tools (Meta, Google, Microsoft, TikTok) for marketing". Output is a web dashboard of trait cards (coffee consumption, chronotype and the like), each with a short research note. For health conditions with effect sizes and study links it is thin; for an entertaining trait tour it is cheap and well made. Read the retention terms before uploading, since the business model depends on keeping your file.

LiveWello

LiveWello sells a one-time Gene Variance Report. Its home page shows no price today (livewello.com, checked 14 October 2026); KnowYourDNA's review, updated 26 March 2026, states "Livewello costs $19.95 one-time" with no subscription and no upsells (knowyourdna.com). The uploaded file is stored on the platform, and the review does not describe retention terms. Reports are organized by category (methylation, detox, cardiovascular, mood, immune) and list SNPs, your genotype and the risk allele, but the review is explicit that "The reports present raw data" and goes on to say they neither interpret results, suggest lifestyle changes nor flag which findings matter most. Accepted files, according to the same review: 23andMe, AncestryDNA, FamilyTreeDNA, MyHeritage and some whole-genome services; livewello.com itself lists no providers. It suits people who already know which rsIDs they want to see and want them in one table; it is not a report you hand to anyone else.

Xcode Life

Xcode Life sells per-topic reports from an uploaded file: individual reports from $30 (Gene Nutrition $40, Gene Health $50, MTHFR and Methylation $69), a Health Pack at $139 and a Genome Pack at $199, with "718 Genetic Traits Analyzed" and results "delivered within 24 hours" (xcode.life, checked 14 October 2026). It accepts 23andMe, AncestryDNA, MyHeritage, FamilyTreeDNA, Living DNA and others. Its privacy summary says raw data is not shared with third parties and that you can delete your raw data and account at any time (privacy summary); retention until then is not stated. The home page advertises "Rated 4.6/5 on Trustpilot" next to "60,000+ reviews" without tying the two together, so read the Trustpilot profile directly. The reports are curated per topic and readable; the evidence behind each row is less transparent than a per-study link.

Genetic Lifehacks

Genetic Lifehacks is a membership library rather than a report: $17.99 per month, $79.99 per year or $179 once for lifetime access to 420+ research articles (membership page, checked 14 October 2026). Your file is read in the browser: "Your data never leaves your device" and is "never uploaded to our servers". Each article highlights your genotype for the variants it discusses and ends with a lifehacks section; printable topic summaries put the flagged variants on one page. Supported files: 23andMe v3 to v5, AncestryDNA, MyHeritage, tellmeGen and others; the page warns that Ancestry "changed its data files in March 2026 and now covers fewer variants". This is the most actionable tool on the list and our pick for reading up on single genes. The trade-offs: a recurring fee unless you buy lifetime access, and no single document per person.

Allelix

Allelix is open source (AGPL-3.0-or-later) and runs on your own computer: "No data leaves your machine. No telemetry. No uploads. No analytics." (pypi.org, version 2.4.2 released 13 October 2026, checked 14 October 2026). It is a Python command-line tool (pip install allelix) with a browser demo at analyze.allelix.io. It reads 23andMe, AncestryDNA, MyHeritage, FamilyTreeDNA, Living DNA and VCF files and annotates them against ClinVar, ClinPGx (CPIC), the GWAS Catalog and SNPedia, writing HTML, JSON or terminal reports (github.com/allelix/allelix). Two honest notes: a freshness check contacts the database sources before analysis unless you pass the no-update flag, and the SNPedia data is licensed for non-commercial use. If you are comfortable in a terminal it is the most auditable tool here, because you can read the code.

How to verify a tool never uploads your file

Every on-device tool on this list makes the same claim, and so do we. It is checkable in under a minute, with the method from our security page:

  1. Open the tool and select your raw file, but do not start yet.
  2. Open the developer tools (F12, or Cmd-Option-I on a Mac) and switch to the Network tab. Tick "Preserve log".
  3. Start the analysis and watch the requests.
  4. Sort by size. Your file is tens of megabytes, so an upload of it shows as a request of roughly that size, usually a POST. Click any large request and read its payload.

On Full Human you will see the generator module download once, and two small requests that reserve and complete a credit; the first carries the report type and nothing else, the second has no body. If a tool claims in-browser processing and a request the size of your file leaves the page, the claim is false. On upload services you will see the upload, which is expected.

For tools that claim no network use at all, go offline after the page has loaded and run the analysis again. Allelix with the no-update flag passes; Full Human does not, because reserving the credit needs a connection, but the file still never leaves the tab.

The same tab shows trackers (facebook.com, tiktok.com, doubleclick.net). We load a Google Ads tag on marketing pages when advertising is running, never on the sign-in or generator pages, so this test shows none; our security page lists every service we use. Genomelink discloses Meta, Google, Microsoft and TikTok tools. Decide from the list, not from the marketing copy.

What a raw file can and cannot tell you

A raw file is a list of a few hundred thousand positions the chip tested, with your genotype at each one. It is not your genome, and every tool above is limited by that.

What it can tell you: your genotype at well-studied common variants such as APOE rs429358 and rs7412, HFE rs1800562, Factor V Leiden rs6025 or the lactase variant rs4988235, and, matched against genome-wide association studies, which common variants you carry that studies associate with higher or lower odds of a condition, with the effect size each study measured. That is what our report does across 23,220 associations, and what Promethease does through SNPedia.

What it cannot tell you: anything about positions the chip did not test, which includes most rare pathogenic variants; a "--" is a no-call, not a result; calls at rare positions on consumer chips are unconfirmed and can be wrong, so a worrying single row needs a confirmatory test first. Candidate-gene SNPs such as MTHFR rs1801133 are in the file but absent from GWAS-based catalogs because they never reached genome-wide significance. Genetic Lifehacks reports that AncestryDNA changed its file in March 2026 and now covers fewer variants (geneticlifehacks.com, checked 14 October 2026); we have not seen a statement from Ancestry. And none of these tools tells you whether you have or will get a condition: odds ratios describe groups, and your baseline risk, family history and lifestyle are not in the file. Talk to a doctor or genetic counsellor before acting on any row.

FAQ

What can I do with my raw DNA data?

You can run it through a health report (Full Human, Promethease, GenomeInsight), look up single genes (Genetic Genie, Genetic Lifehacks, LiveWello), explore traits (Genomelink) or analyze it offline with open-source software (Allelix). Genealogy matching takes the same file but is outside this article. Each use is a separate decision about where a copy of the file goes.

Is it safe to upload raw DNA data?

It depends on the service. A raw file identifies you and your relatives and cannot be changed later. Before uploading, read the retention and deletion terms, check whether the file is listed as a transferable asset, and prefer tools that read the file in your browser. If you would not be comfortable deleting the account later, do not upload now.

Can raw DNA data tell me about my health?

Partly. Matched against genome-wide association studies, the file shows which common variants you carry that are associated with higher or lower odds of a condition, with the effect size reported. It cannot confirm rare variants, does not include your baseline risk or family history, and is not a clinical test. Treat any row as a prompt for a conversation with a doctor or genetic counsellor.

What is the first thing to do with raw DNA data?

Download it and store it in two places, ideally encrypted. Our download guide covers 23andMe, AncestryDNA and MyHeritage. Then decide what you want to know and pick one tool for that question, rather than uploading the file to five sites at once. Tools that read the file in your browser do not add a copy anywhere.

Which tools work with MyHeritage files?

MyHeritage exports a .csv that Full Human, Genetic Genie, GenomeInsight, SelfDecode, Genomelink, Xcode Life, Genetic Lifehacks and Allelix list as supported, and that Sequencing.com and LiveWello accept according to KnowYourDNA. The DNA Complete upload takes 23andMe and AncestryDNA files only, and promethease.com does not show MyHeritage among its sample reports, so check before paying.

This article is for general information only and is not medical advice. Talk to a qualified healthcare professional before making health decisions based on genetic data.

The alternative that stays on your device

Same raw file. One readable PDF. Nothing uploaded.

Full Human reads the 23andMe, AncestryDNA or MyHeritage file you already have in your browser and writes a 17-section PDF with a PubMed link on every row.

1114 conditions and traits · 17 sections · GWAS Catalog June 2026

Your DNA file stays on your device during report generation.

Topicsraw DNA dataDNA analysis toolsPrometheaseSelfDecodeprivacyGWAS Catalog