No, 23andMe is not gone: it still sells kits under a nonprofit owner. But if you already have a 23andMe, AncestryDNA or MyHeritage raw data file, you do not need a new kit to get health reports. Most of the options below read that file. We compare eight of them by price, whether a new sample is needed and where your DNA goes.
Is 23andMe shutting down?
Status, October 2026. 23andMe filed for Chapter 11 on 23 March 2025. TTAM Research Institute, Anne Wojcicki's nonprofit, bought the consumer business out of bankruptcy: Regeneron's $256 million offer was outbid by TTAM's $305 million (BioSpace, 16 June 2025, checked 14 October 2026). The sale closed on 14 July 2025 and 23andMe "is continuing to operate" (23andMe press release, 14 July 2025, checked 14 October 2026). The site now lives at 23andme.org, whose About page is titled 23andMe Research Institute (checked 14 October 2026). Raw-data downloads still work. Full timeline: our review of the 23andMe bankruptcy.
Two kinds of alternative: a new kit, or a report from the file you already have
Most lists of 23andMe alternatives are kits to buy. That is the right list if you have never been tested, or if you want relative matching rather than health content. It is the wrong list if you have already spat in a tube once. Your raw data file holds hundreds of thousands of genotyped positions, and that file is what every third-party health tool reads. A second genealogy kit gives you a second copy of much the same data and, in most cases, no health reports at all.
Two questions settle the choice:
- Do you already have a raw data file? If yes, download it now, while the account is yours to control. Our guide to downloading raw DNA data covers 23andMe, AncestryDNA and MyHeritage step by step.
- Do you want health content, genealogy, or both? Health reports from your existing file start at $5. Genealogy kits start around $90. Whole-genome sequencing starts at $245 and needs a new sample.
Eight 23andMe alternatives compared
| Option | Price | New sample? | Health content | Where your DNA goes |
|---|---|---|---|---|
| Full Human Health | $5 per PDF, no subscription | No, reads your file | 1,114 conditions and traits from the GWAS Catalog, 17 categories, PubMed link on every row | Stays in your browser; nothing is uploaded |
| Promethease | $25 per report, $4 per extra file | No | SNPedia literature list: conditions, drug responses, traits | Uploaded; deleted after the report is emailed |
| GenomeInsight | Free tier, $49 one-time | No | Traits, conditions, medication scanner | Runs in the browser; trackers reported on the site |
| Genetic Genie | Free, donations welcome | No | Methylation and detox panels, ClinVar variant lookup | Uploaded; the site says it is not stored |
| SelfDecode | $319 to upload a file; $499 to $899 bundles with kit | No for upload; yes for bundles | 1,500+ reports, polygenic scores, recommendations | Uploaded and stored |
| Nebula Genomics DNA Complete | $245 (1X) and $595 (30X), shown as sale prices | Yes, cheek swab | Whole-genome sequencing with reports | New sample sequenced and stored |
| AncestryDNA, MyHeritage DNA | $99 and $89 list price, often discounted | Yes | None: genealogy only | New sample stored |
| Living DNA | Kits from $90; upload free | Kit yes; upload no | Wellbeing upgrade, if your file has enough markers | Uploaded |
Prices, dates and quotations in this article were checked on 14 October 2026 on the pages linked.
Full Human Health is our tool, so weigh this paragraph accordingly. You open your 23andMe, AncestryDNA, MyHeritage, FamilyTreeDNA, Living DNA or WeGene file in the browser, and a generator written in Rust and compiled to WebAssembly writes the PDF on your device. One credit is one PDF: $5, no subscription, and a failed generation is refunded automatically. It does not cover ancestry, carrier status, pharmacogenomics or rare pathogenic variants. The sample report is a real extract.
Promethease costs $25 per report plus $4 per extra file (promethease.com). You upload the file and receive a long, dense list of SNPedia entries, and SNPedia has been "not as actively updated since ~2019" according to Genetic Lifehacks' 2026 guide. More tools are compared in Promethease alternatives.
GenomeInsight has a free tier with 30 traits and a $49 one-time plan, and says "all analysis runs in your browser" (pricing page). Its medication scanner is something we do not offer. One caveat: the same Genetic Lifehacks guide reports Facebook and Google trackers on the site despite its stated policy.
Genetic Genie is free, needs no account, and covers methylation and detox panels plus a ClinVar-based variant lookup (GenVue Discovery) that reads 23andMe, AncestryDNA and sequencing files (geneticgenie.org, checked 14 October 2026). The file is uploaded and, the site says, not stored. It is the right tool if MTHFR and COMT are what you want to see: those candidate-gene variants never reached genome-wide significance and are not in a GWAS-based report like ours.
SelfDecode is the broadest platform of the group, with polygenic scores and lifestyle recommendations. Uploading an existing file costs $319 and "uploaded DNA files do not include all SelfDecode features and reports" (upload page); kit bundles run $499 to $899 (selfdecode.com), and prices for new purchases rose on 28 August 2026 (help centre). Your data lives on their servers.
Nebula Genomics DNA Complete sequences a new cheek-swab sample: $245 for 1X and $595 for 30X, shown as discounts from $395 and $895 when we checked on 14 October 2026 (nebula.org/dnacomplete). KnowYourDNA reported the original consumer service shut on 5 February 2025 (KnowYourDNA), so read recent reviews on delivery times before ordering.
AncestryDNA and MyHeritage DNA are genealogy kits. Ancestry announced in January 2021 that it was discontinuing AncestryHealth, a decision its help centre dates to "the winter of 2020", and supported the reports through July 2021 (Ancestry help centre, checked 14 October 2026). MyHeritage stopped accepting third-party uploads "as of August 2025" (MyHeritage, checked 14 October 2026). MyHeritage showed CHF 29 instead of CHF 89 when we checked from Switzerland (myheritage.ch, checked 14 October 2026); third-party reviews put Ancestry's US list price at $99 at the time of writing (KnowYourDNA, updated 21 August 2026). Buy one for relative matching, not for health.
Living DNA sells kits from $90 plus shipping, or $179 with its Wellbeing report (livingdna.com). It also accepts free uploads from 23andMe, AncestryDNA and MyHeritage, lists FamilyTreeDNA among the formats it reads, and offers a paid wellbeing upgrade only "if your original DNA provider tested for the majority of SNP markers required" (upload page, checked 14 October 2026). The upgrade price is not published.
What 23andMe's health reports covered, and what a GWAS report covers instead
23andMe's health reports are FDA-authorized tests for named variants. The 2017 authorization covered Genetic Health Risk reports for ten conditions, among them late-onset Alzheimer's, Parkinson's, celiac disease and hereditary hemochromatosis (FDA, direct-to-consumer tests, checked 14 October 2026). The BRCA1/BRCA2 report started with three variants in March 2018 (23andMe, checked 14 October 2026) and was cleared for 44 variants on 31 August 2023 (510(k) K223597, checked 14 October 2026). Carrier status reports (first authorized on 19 February 2015, for Bloom syndrome) and pharmacogenetic reports (31 October 2018) went through the same FDA review (FDA De Novo DEN140044 and DEN180028, checked 14 October 2026). The FDA's wording matters: these tests "do not determine a person's overall risk of developing a disease or condition", and after a negative result a person "still may be at risk". Each report answers one narrow question with a validated assay. 23andMe+ Premium covers "45+ conditions" for $199 then $69 a year, and Total Health "90+ conditions" for $499 then $199 a year, according to KnowYourDNA's review (updated 21 August 2026), as 23andMe's US shop is not shown from Europe.
A GWAS-based report answers a different question. The GWAS Catalog records associations from genome-wide studies: this variant is more common in people with condition X, with this odds ratio. Our health catalog keeps 23,220 such associations across 1,114 conditions and traits from 1,459 studies, filtered to genome-wide significance (p < 5×10⁻⁸). For each condition the report lists the risk alleles you carry, combines their odds ratios and gives a verdict of higher, lower or average risk, explained in plain language. The methodology page spells out the limits: no zygosity weighting, no linkage-disequilibrium correction, no baseline risk, and not a clinical polygenic risk score.
So the trade is width for depth. 23andMe tells you with a validated assay whether you carry 44 specific BRCA variants; a GWAS report does not interpret BRCA pathogenic variants at all. A GWAS report tells you what some 1,660 prostate cancer associations or 482 Alzheimer's associations say about your genotype; 23andMe's Alzheimer's report is built on one variant, APOE ε4. Neither is a diagnosis. If a row worries you, take the PDF to a doctor or genetic counsellor; every row links to the study behind it, so they can check it.
Privacy: where your file goes
- Stays on your device: Full Human (nothing is uploaded; the security page shows how to verify that yourself) and GenomeInsight (in-browser analysis, with the tracker caveat above).
- Uploaded, then deleted: Promethease (its privacy page says files are deleted after the report is emailed, and all stored files were deleted on 8 April 2025) and Genetic Genie (not stored, by its own account).
- Uploaded and stored: SelfDecode, Living DNA uploads, Nebula sequencing, and every new kit, 23andMe included.
The stored category is where 23andMe's history matters. The 2023 credential-stuffing breach led the UK Information Commissioner to fine 23andMe £2.31 million on 17 June 2025 for failing to protect the data of 155,592 UK residents (ICO, checked 14 October 2026), and California's Attorney General sued the former company, now Chrome Holding Co., on 28 May 2026 over the same breach (California DOJ, checked 14 October 2026). None of this makes a given competitor unsafe. It means that a file that never leaves your device has nothing to breach, and nothing to delete when a company changes hands.
If you are in the UK, Ireland or the EU
At the time of writing, 23andMe sells its health reports only in the United States, Canada, the United Kingdom, Ireland, Denmark, Finland, the Netherlands and Sweden. Its international help centre lists the countries where Carrier Status, Health Predisposition and Wellness reports are not available, Germany, France, Switzerland, Austria, Italy and Spain among them, and says that customers there receive "Ancestry Reports, Traits Reports, and uninterpreted raw genetic data" (23andMe help centre, checked 14 October 2026). From Switzerland, 23andme.org offered only the Ancestry Service, at USD 119. If you live elsewhere in Europe, that is the main reason to look at your raw file instead of a new kit: a file from any provider works the same way in a third-party tool.
Two legal notes, not legal advice. Germany's Gendiagnostikgesetz reserves health-related genetic testing for physicians, which is why no German company offers direct-to-consumer health interpretation. France prohibits recreational DNA tests under article 226-28-1 of the Code pénal, and 23andMe, Ancestry, FamilyTreeDNA and MyHeritage no longer ship kits there according to AFP (16 April 2025). Check your own situation. Our reports are priced at €5, £5 and CHF 5, generated in the browser, and available in English, German and French.
How to switch without a new kit
- Download your raw data. In 23andMe, open Settings, then 23andMe Data. Ancestry emails a download link that expires after 7 days. The download guide has the steps for each provider.
- Keep an encrypted copy in two places. The file cannot be reissued if the account disappears.
- Pick a tool from the table using the two questions above.
- Read a sample before you pay. Ours is the sample report; Promethease and SelfDecode publish demo reports too.
Whether to delete your 23andMe account afterwards is a separate decision; the bankruptcy review covers those steps.
FAQ
Is 23andMe going out of business?
No. 23andMe filed for Chapter 11 in March 2025, but its consumer business was bought out of bankruptcy by TTAM Research Institute, and the sale closed on 14 July 2025. The company says it is continuing to operate, and kits are still sold at 23andme.org. The risk for customers is not a shutdown but a change of terms, so download your raw data either way.
Who owns 23andMe now?
TTAM Research Institute, a nonprofit public benefit corporation founded and led by 23andMe co-founder Anne Wojcicki. It paid $305 million for the Personal Genome Service and research business lines. The website now presents it as the 23andMe Research Institute. In the sale announcement, TTAM committed to keep the privacy policy and customers' right to delete their data and opt out of research (23andMe, 13 June 2025, checked 14 October 2026).
Did 23andMe sell data to Regeneron?
No. Regeneron was announced as the winning bidder in May 2025 with a $256 million offer, but the auction was reopened and TTAM outbid it with $305 million. Regeneron declined to raise its bid and became the backup bidder. The sale that closed in July 2025 went to TTAM, not to a pharmaceutical company.
What is the best 23andMe alternative for health?
It depends on what you already have. With a raw data file, a $5 GWAS-based PDF from us, a $25 Promethease report or GenomeInsight's $49 plan all work without a new kit. If you want the broadest platform and accept that your data is uploaded and stored, SelfDecode covers the most ground. If you have no file at all, Nebula sequences a new sample.
Can I get health reports from AncestryDNA data?
Yes. Ancestry dropped its own health product in January 2021, but the raw file you download from Ancestry works in Full Human, Promethease, GenomeInsight, Genetic Genie and SelfDecode. Genetic Lifehacks reported that Ancestry changed its file format in March 2026 and that newer files contain fewer markers, so coverage may be lower; treat that as a reported change, not a settled fact.
This article is for general information only and is not medical advice. Talk to a qualified healthcare professional before making health decisions based on genetic data.
The alternative that stays on your device
Same raw file. One readable PDF. Nothing uploaded.
Full Human reads the 23andMe, AncestryDNA or MyHeritage file you already have in your browser and writes a 17-section PDF with a PubMed link on every row.
1114 conditions and traits · 17 sections · GWAS Catalog June 2026
Your DNA file stays on your device during report generation.